HydealCyst
An effective treatment for recurrent urinary tract infections or interstitial cystitis. HydealCyst is an intervesical instillation with the highest dose of Hyaluronic Acid.
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HydealCyst is a bladder instillation and consists of a unique combination of Hydeal-D and Hyaluronic acid. Hyaluronic acid is an important substance in the GAG layer that provides protection for the bladder. HydealCyst restores the GAG layer and protects against symptoms that occur in bladder pain syndrome, (recurrent) urinary tract infections and radiocystitis.
Hyaluronic acid in HydealCyst restores the GAG layer, has anti-inflammatory effects and increases the protective mechanisms of the epithelium.
Due to the unique combination of Hyaluronic acid and Hydeal-D, HydealCyst provides long-term protection of the bladder.
HydealCyst
Intravesical instillation with 1,000mg Hyaluronic acid + Hydeal-D
- New Formulation
- High muco-adhesiveness
- Extended release
- Increases the natural secretion of the antimicrobial peptide β-defensin6
Recurrent urinary tract infections
- Effective prophylaxis in recurrent urinary tract infections
- Intravesical treatment with Hyaluronic Acid improves quality of life
- There is a strong association between recurrent urinary tract infections and sexual dysfunction. Studies show that treatment with intravesical hyaluronic acid leads to an improvement in symptoms and an improvement in sexual dysfunction that persisted for up to 12 months
- HA instillations reduce the number of recurrent urinary tract infections in patients with Spina Bifida and a neurogenic bladder who perform clean intermittent catheterization. It is a safe and effective treatment
Interstitial cystitis/bladder pain syndrome
- Intravesical installations with high molecular weight Hyaluronic Acid is superior in effectiveness and cost over other instillation therapies
- Intravesical Hyaluronic Acid administrations lead to a reduction in IC symptoms, bladder pain and urinary frequency after four instillations, after completion of nine instillations, nocturia was reduced and bladder capacity increased. Low-grade glomerulation predicts successful outcome
- Previous treatment modalities and the presence of Hunner’s lesions do not affect the efficacy of HA instillation
- Intravesical HA instillation improved pain symptoms, quality of life, bladder volume and voided urine volume
- Intravesical HA instillation prolonged the effect of bladder hydrodistension in patients with severe interstitial cystitis. The effect of HA was better than Heparin
Dosage
Apply HydealCyst once per week for 4 weeks.
Then one instillation per month.
Usage
Wash hands thoroughly before application and follow the procedure below:
- Insert a bladder catheter with Luer-Lock connection into the bladder under sterile conditions
- Remove the remaining urine
- Remove the syringe from the pouch with the specific opening
- Remove the cap from the pre-filled syringe and connect the syringe to the catheter
- Instill the solution of 50 ml of protected preparation into the empty bladder
- After instillation, remove the catheter
- The protective solution should be kept in the bladder as long as possible, from at least 30 minutes to 2 hours.
To alleviate symptoms related to the condition, it is recommended to instill the protective solution into the bladder once a week for 4 weeks
. Then, and only on doctor’s advice, administration may be made less regularly once every two weeks or once a month until symptoms have resolved. The physician should monitor any prophylactic use of HydealCyst.
